Over the past decade, the complexity of clinical development protocols has increased significantly. Sponsors are running more studies simultaneously, across more geographies, and with increasingly specific patient populations. Yet in many cases, recruitment strategies are still built around individual protocols rather than the broader clinical portfolio.
From an operational perspective, this creates inefficiencies that slow down timelines and increase costs. Teams repeatedly launch separate campaigns, develop new recruitment materials, and rebuild infrastructure. While each protocol may be managed effectively on its own, the overall system often lacks scalability.
At Clariness, we work closely with sponsors navigating these challenges daily. What we consistently see is a growing need to move beyond isolated recruitment efforts toward more integrated, portfolio-level solutions.
Enterprise Trial Solutions was developed with this operational reality in mind. Instead of treating recruitment as a series of disconnected activities, it provides a structured framework that allows sponsors to scale recruitment, streamline creative production, and activate patient engagement channels more efficiently across their clinical pipelines.
~ Janine Hart, Chief Operating & Compliance Officer, Managing Director

Clinical trial patient recruitment has long been one of the most complex and resource-intensive parts of the development process. Sponsors often manage recruitment separately for every protocol, leading to duplicated efforts, fragmented strategies, and unnecessary delays.
As clinical pipelines expand and portfolios grow, this traditional approach becomes increasingly inefficient. Sponsors need scalable solutions that can support multiple studies simultaneously while reducing operational burden.
Clariness’ Enterprise Trial Solutions was designed to address this challenge.
Following our recent merger with Subject Well, we are now able to support sponsors at a new scale. By combining scalable recruitment, centralized creative production, and rapid activation channels, Enterprise Trial Solutions helps sponsors streamline recruitment across their clinical portfolios, saving time, reducing costs, and accelerating timelines.
The approach consists of three complementary solutions designed to support clinical programs at different stages of recruitment.
1. Enrollment at Scale
Many organizations still approach recruitment study by study. Each new protocol requires launching new screeners, building new campaigns, and investing in fresh media strategies.
While this approach works for single trials, it becomes inefficient where cohort overlap can be leveraged or where a product is seeking approval in multiple indications.
Enrollment at Scale takes a portfolio-level approach. Instead of running independent recruitment efforts for each protocol, it enables sponsors to recruit patients across multiple studies through a unified strategy.
By unifying recruitment under one outreach budget and implementing a screening step that guides patients to the most suitable study, sponsors can leverage shared patient engagement infrastructure to reduce operational duplication and significantly lower recruitment costs.
In fact, this approach can reduce recruitment costs by up to 50% per randomized patient while accelerating patient identification across studies.
2. Creatives Lab
Patient recruitment requires a wide range of clinical trial branding materials including digital ads, landing pages, patient education assets, and campaign visuals.
When these materials are managed independently for each study, teams often face:
- Repeated production processes
- Multiple approval cycles
- Inconsistent branding across campaigns
- Increased operational workload
Creatives Lab centralizes and streamlines the production of recruitment materials across an entire clinical portfolio.
With a structured and standardized creative process, sponsors can maintain brand consistency while significantly reducing production time and resource demands.
This centralized approach can lead to up to 30% savings in time and costs, while enabling faster campaign launches and more efficient collaboration between teams.
3. Marketplace Recruitment
Even with well-planned recruitment strategies, some studies still struggle to meet enrollment timelines. Traditional recruitment campaigns can take up to three months to fully launch, which can be problematic when timelines begin to slip.
Marketplace Recruitment offers a faster alternative.
Through ClinLife®, Clariness’ global patient recruitment platform, sponsors can showcase their studies to millions of patients actively searching for clinical trials.
This solution enables rapid activation, with campaigns going live in as little as two weeks. By connecting studies directly with motivated patients, Marketplace Recruitment provides an efficient way to boost enrollment and maintain study momentum.
A portfolio-driven approach to recruitment
Clinical pipelines are becoming more complex, and recruitment strategies must evolve accordingly. Managing recruitment separately for each study is no longer sustainable for large portfolios.
Enterprise Trial Solutions offers a more scalable model, combining recruitment strategy, creative production, and patient engagement into a coordinated ecosystem.
By approaching recruitment at the portfolio level rather than the individual study level, sponsors can accelerate timelines, reduce costs, and improve operational efficiency across their clinical programs.
What’s next?
In upcoming articles, we’ll explore each of these solutions in greater depth:
- How Enrollment at Scale transforms recruitment strategy for multi-study portfolios
- How Creatives Lab streamlines campaign production and ensures brand consistency
- How Marketplace Recruitment accelerates enrollment through direct patient engagement
Together, these solutions represent a new way of thinking about clinical trial recruitment, one built for the scale and speed of modern clinical development.
For more than 20 years, Clariness has supported sponsors and research sites in navigating the complexities of clinical trial patient recruitment in over 400 indications. Our global solutions have benefited over 8,000 sites with patients and supported over 28,000 randomizations. By combining advanced technology, global patient outreach, and operational expertise, Clariness helps sponsors streamline recruitment and improve enrollment.
Learn how Enterprise Trial Solutions can accelerate your clinical trials.