Need help accelerating your study?
Need help accelerating your study?
Depression is estimated to affect 264 million people worldwide, yet trials still face problems with recruitment.
Depression is set to become the world’s largest health problem and primary cause of disability by 2030, surpassing cardiovascular disease, cancer, and diabetes. Despite affecting mainly young people online, it remains difficult to reach and enroll them in clinical trials, posing a challenge for organizers. Targeting the right audience is also crucial to reduce placebo response rates.
Having supported 10+ psychiatric studies (from Phase I-IV). With our multichannel digital marketing approach (that covers 40+ channels), patient insight expertise, depression community analysis and study protocol reviews, we can solve your patient recruitment challenges.
Addressing patient diversity
Minority groups are underrepresented in all clinical trials, including studies on depression. In recent years, research has increasingly focused on including ethnic minorities, people with different gender identities, and trauma survivors in clinical trials on mental illnesses, such as depression. To date, however, these efforts have not been overly successful – despite the fact that ethnic minorities are increasingly seeking professional help for their condition. For example, in the USA, there was a large increase in Asian and Pacific Islander (17% increase in the study population), as well as Native Americans (7.5% increase) and African Americans (6.89% increase) seeking help for their depression in 2020.
Sponsors of clinical trials in depression have increasingly sought to globalize their studies over the past decade. Including patients and physicians worldwide addresses patient diversity, increases patient recruitment in many developing countries, and allows for earlier access to new therapies and medications. Patients with depression in developing countries typically do not have adequate access to treatments and are less likely to have used existing antidepressants. This also means these patients may respond better to newly developed antidepressants as they are naive to current treatments.
We help identify and reach a diverse patient population with customized languages, study information, and study advertisements. In this way, we are able to recruit a representative population for your depression studies.
Based on patient insights, we can reach a more diverse patient population with our patient recruitment and retention services.. We use digital tools and multiple communication channels to reduce physical barriers to accessing the study site, create patient-friendly study materials to increase health literacy, and adapt our strategies to local communities and cultures.
By understanding patient needs, we can overcome the unique barriers these patients face when enrolling or participating in clinical trials.
Our digital targeting techniques
Age, social media behavior and profile, and other demographic indicators are used as filters to find people with depression (and their families) that are most likely to match your study.
Age, in particular, is an important factor. Where major depression affects more people between the ages of 45 and 65, severe depression is more likely to affect the very young and very old.
Low socioeconomic status has also been linked to a higher prevalence of depression (based on education, rather than income; Freeman, 2016).
Location & capacity targeting
We consider geographic variation in depression prevalence. Therefore, patients living within a predesignated radius around active sites are targeted with ads that are activated and deactivated based on site referral volume.
For example: In the USA, researchers conclude that there is no significant difference between the prevalence of depression in rural areas and cities. However, in Germany, rural areas with a low population density showed the highest prevalence (+34%), while big urban municipalities showed the lowest (+25%).
Gender, ethnicity, socioeconomic People with depression are primarily young and active online. Through forums, social media groups, and events, we reach out and explain the processes and potential benefits of participating in clinical trials.
Database & Behavioral targeting
We send study notifications to our large database (>1.3 million registered ClinLife users worldwide) based on their location and indication details. By continuously analyzing the (anonymized) behavior of those who were successfully enrolled, we can understand and reach similar people.
Are you designing a depression study, or have one underway?
We can help you find the right patients, at the right time. To find out more about our depression patient recruitment, contact us.