Patient recruitment for Alzheimer’s disease clinical trials

Alzheimer’s disease

Connect with Alzheimer’s patients across the globe​

Globally, almost 10 million new cases of dementia are diagnosed every year, with Alzheimer’s disease accounting for 60-70% of cases.

While the number of diagnosed patients continues to grow, clinical trials on Alzheimer’s disease in particular are facing a critical shortfall of eligible patients. We’ve performed Alzheimer’s disease patient recruitment for 10+ international trials, from Phase II to Phase III – we know how to find the right candidates for your study.

1 m

new cases each year

1 +

international trials (phase II & III)

1 +
1

million people diagnosed with diabetes  worldwide (2021)

Challenges when recruiting patients for diabetes studies

50% (232 million) of people with diabetes are undiagnosed (according to the International Diabetes Federation).

Therefore, it is hard to reach patients without specific outreach methods.

Newly diagnosed people often do not feel sick or in need of treatment.

Studies show that many patients (especially from minority groups) do not know about diabetes symptoms due to less access to healthcare, education, and lower socioeconomic status. Another barrier is what researchers describe as ‘Diabetes Denial,’ meaning many patients ignore mild symptoms.

Many trials do not provide patient-centric information.

Details on inclusion and exclusion criteria, the goals and procedure of the study, and other information are often not provided in a patient-centric manner. This leads to lower sign-up and participation rates, as well as higher drop-out during a clinical trial.

0 %

18-44 years of age

0%
18-44 years of age
0 %

45-64 years of age​

0 %

>65 years of age​

Alzheimer’s disease

Reach patients and caregivers across the globe

Those within the early stages of Alzheimer’s disease wish to hold onto their independence for as long as possible, while those further along require additional care and are more difficult to reach and engage.

That’s why at Clariness, we target both patients and caregivers, which provides much higher engagement and participation willingness. In fact, within a recent survey of 600 participants across 21 countries, 85% of respondents were caregivers.

Alzheimer’s disease

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Alzheimer’s disease

Special screening techniques

Our targeting techniques drive high volumes of traffic to our customized screeners, leading to higher numbers of referred and randomized patients for Alzheimer’s disease studies.

For example, one campaign drove 800k+ visits to our screener that consisted of multiple questions assessing medical eligibility, including I/E criteria, diagnosis, and symptoms.

Ensuring a high scheduling rate, we also provide a customized phone screener that covers participation willingness and a detailed assessment of medication history. This helps to limit study delays and ensures more consented and randomized patients.

Alzheimer’s disease

Find patients aligned to your protocol

Most patients with Alzheimer’s disease are 65+ years old – although early-onset Alzheimer’s can develop earlier.

We reach patients with mild to severe stages of Alzheimer’s disease, as well as their caregivers. We target these patients at stages within their lives where Alzheimer’s is most common.

Our Chief Medical Officer reviews your protocol and aligns with our patient recruitment team. We develop and create objectives and tactics to ensure that patients referred to your sites fit the exact requirements of your study.

How we can help

How can Clariness support my dermatology studies?

We have several options:

1. List your study on our global patient portal, ClinLife®

ClinLife® is a free platform that connects patients worldwide with clinical trials relevant to their medical conditions. Studies are organized by disease area or condition, allowing patients to easily find trials that match their needs.

2. List your study on ClinLife® and launch a tailored recruitment campaign

Maximize your study’s reach with a customized recruitment campaign. We’ll list your study across 40+ online channels and deliver geo-targeted ads to engage patients near your trial sites.

Interested in a strategy session to discuss how we can tailor a campaign for you?
Clariness is the recruitment solution of the future.
Study Coordinator, Department of Cardiology, Clinic Maria Hilf GmbH
We are very happy with the service and wish the recruitment campaign hadn’t ended so soon.
Study Coordinator, St. Johanes Hospital
We have a very large patient database but it is much easier to use Clariness referrals.
Clinical Study Coordinator, Asklepios MVZ Bayern – Landsberg
Clariness has supported us in patient recruitment in nine studies across six different indications, accelerating recruitment, and increasing screening and randomization numbers. Referrals have been constant and consistent, so we’re excited to see the results of continuing patient recruitment through the ClinLife® Registry.
Principal Investigator, Velocity Berlin
Clariness perform the pre-screening and get lots of information for us, before we contact the patient. It really helps us as we’re a tiny department that does a lot, so anything that helps is appreciated.
Human Research Protection Program Coordinator
It’s a bit like magic – we don’t have to do anything and suddenly, we have a list of interested participants!
Clinical Trials Manager
“I usually never click on ads, but this ad about a clinical trial really appealed to me, so I applied right away. The research center was only 2 km away, so the personal approach was optimal.”

2021 Patient’s Voice participant

Explore insights

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How we can help

Our services and solutions

Leverage our experts, data and platforms, to accelerate your clinical trials

Demographic

Location

Interest

Database

Services & Solutions

Addressing patient diversity

Minorities are underrepresented in all clinical trials, including many vaccine trials. 

Historically, marginalized populations are underrepresented in Alzheimer’s disease clinical trials – despite evidence that these populations may be at increased risk of developing dementia. These include patients that identify as racial or ethnic minorities and those with low socioeconomic status or are living in rural areas.

Informed by Patient Insights, our Alzheimer’s disease patient recruitment and retention services allow us to reach a more diverse population. We use digital tools and multiple communication channels to reduce physical barriers to site access, create patient-friendly study materials to increase health literacy, and tailor strategies to local communities and cultures.

By understanding patient needs, we can overcome the unique barriers these patients face when joining clinical trials.

Services & Solutions

Find patients aligned to your protocol

Embracing new decentralized clinical trial (DCT) solutions in your clinical trial improves the diagnosis and assessment of Alzheimer’s disease.

Recent research shows that wearables, unobtrusive sensors, or other digital technologies enables continuous real-world data collection that captures subtle changes in cognition and functional capacity of patients. These technologies improve trial timelines by better identifying suitable patients for trials (at earlier stages of their Alzheimer’s disease) and improving assessment of disease progression and treatment response throughout the trial. Digital technologies also enhance patient care and safety, while providing caregivers with an additional tool to look after their patients. We can help you adopt new approaches and transform your trial by, for example, navigating regulatory changes, creating study materials for patients and caregivers to better understand new technologies, and providing intensified support to sites to reduce site burden. Our experience with hybrid and DCTs can be applied directly to your study.

Case study

Our diabetes case studies

Learn how we’ve supported sponsors with their patient recruitment for diabetes studies, across the globe, resulting in more engagement, more referrals, at less than the budgeted costs:​

Please note that we will not share your data with any 3rd parties, data submitted will be used in accordance with our data privacy policy.

Contact us

Are you designing a diabetes clinical trial, or have one underway?

We can help you find the right patients, at the right time. To find out more about our heart failure patient recruitment, contact us.